Tesofensine is a serotonin noradrenaline dopamine reuptake inhibitor (SNDRI) from the phenyltropane family of drugs. It was originally developed for the treatment of Alzheimer’s and Parkinson’s disease, but it lacked efficacy for these conditions. However, it has shown potential in the treatment of obesity due to its ability to suppress appetite.
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[1] https://www.sciencedirect.com/ science/article/abs/pii/S0924977X13003003
[2] https://www.researchgate.net/ publication/44608733
[3] https://onlinelibrary.wiley.com/ doi/pdf/10.1038/oby.2011.197
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