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Human Menopausal Gonadotropin (HMG), a peptide hormone, is a complex bioactive compound derived from the urine of post-menopausal women. It primarily comprises Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), and a small concentration of Thyroid Stimulating Hormone (TSH).

HMG plays an instrumental role in the regulation of the reproductive system. The FSH component of HMG interacts with specific receptors on the granulosa cells of the ovarian follicles, stimulating their development and maturation. Concurrently, the LH component of HMG stimulates ovulation via interaction with LH receptors, making it a crucial player in female fertility.

In males, HMG promotes spermatogenesis through its interaction with LH receptors on Leydig cells and FSH receptors on Sertoli cells. Thus, it has potential therapeutic applications in treating male infertility.

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Potential Benefits of HMG Peptide

Stimulation of Ovulation: HMG stimulates the ovaries to produce eggs and is often used in assisted reproductive technologies such as in-vitro fertilization (IVF). It acts directly on the ovaries to stimulate the development and maturation of ovarian follicles [1].
Treatment of Male Infertility: In men, HMG can stimulate the testes to produce sperm. It’s often used in the treatment of male infertility due to hypogonadotropic hypogonadism, a condition characterized by low levels of certain hormones required for sperm production [2].
Combined Therapy: HMG is often used in combination with other hormones such as Human Chorionic Gonadotropin (hCG) to increase the chances of conception. This combination therapy can stimulate both the growth and release of a mature egg [3].
Hormone Replacement Therapy: In postmenopausal women, HMG may be used as part of hormone replacement therapy to manage symptoms associated with menopause [4].

References

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5601935/

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4708300/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5906949/

[4] https://pubmed.ncbi.nlm.nih.gov/9651906/

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HMG

HMG 75iu – Pre Mixed

HMG Nasal Spray

Potential Benefits of HMG Peptide

References